Preclinical

Habringer, S., Lapa, C., Herhaus, P., Schottelius, M., Istvanffy, R., Steiger, K., Slotta-Huspenina, J., Schirbel, A., Hänscheid, H., Kircher, S., Buck, A. K., Götze, K., Vick, B., Jeremias, I., Schwaiger, M., Peschel, C., Oostendorp, R., Wester, H.-J., Grigoleit, G.-U., & Keller, U. (2018). Dual Targeting of Acute Leukemia and Supporting Niche by CXCR4-Directed Theranostics. Theranostics, 8(2), 369–383. https://doi.org/10.7150/thno.21397

Li, J., Peng, C., Guo, Z., Shi, C., Zhuang, R., Hong, X., Wang, X., Xu, D., Zhang, P., Zhang, D., Liu, T., Su, X., & Zhang, X. (2018). Radioiodinated Pentixather for SPECT Imaging of Expression of the Chemokine Receptor CXCR4 in Rat Myocardial-Infarction-Reperfusion Models. Analytical Chemistry, 90(15), 9614–9620. https://doi.org/10.1021/acs.analchem.8b02553

Schottelius, M., Osl, T., Poschenrieder, A., Hoffmann, F., Beykan, S., Hänscheid, H., Schirbel, A., Buck, A. K., Kropf, S., Schwaiger, M., Keller, U., Lassmann, M., & Wester, H.-J. (2017). [177Lu]pentixather: Comprehensive Preclinical Characterization of a First CXCR4-directed Endoradiotherapeutic Agent. Theranostics, 7(9), 2350–2362. https://doi.org/10.7150/thno.19119

Oncology

Demirkol, M. O., Özkan, A., Uçar, B., Wester, H.-J., & Ferhanoglu, B. (2021). Extramedullary Relapsed Multiple Myeloma Treatment With 177Lu-Labeled CXCR4 Endoradiotherapy and Dosimetric Results. Clinical Nuclear Medicine, Publish Ahead of Print. https://doi.org/10.1097/RLU.0000000000003705

Habringer, S., Lapa, C., Herhaus, P., Schottelius, M., Istvanffy, R., Steiger, K., Slotta-Huspenina, J., Schirbel, A., Hänscheid, H., Kircher, S., Buck, A. K., Götze, K., Vick, B., Jeremias, I., Schwaiger, M., Peschel, C., Oostendorp, R., Wester, H.-J., Grigoleit, G.-U., & Keller, U. (2018). Dual Targeting of Acute Leukemia and Supporting Niche by CXCR4-Directed Theranostics. Theranostics, 8(2), 369–383. https://doi.org/10.7150/thno.21397

Herrmann, K., Schottelius, M., Lapa, C., Osl, T., Poschenrieder, A., Hänscheid, H., Lückerath, K., Schreder, M., Bluemel, C., Knott, M., Keller, U., Schirbel, A., Samnick, S., Lassmann, M., Kropf, S., Buck, A. K., Einsele, H., Wester, H.-J., & Knop, S. (2016). First-in-Human Experience of CXCR4-Directed Endoradiotherapy with 177Lu- and 90Y-Labeled Pentixather in Advanced-Stage Multiple Myeloma with Extensive Intra- and Extramedullary Disease. Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine, 57(2), 248–251. https://doi.org/10.2967/jnumed.115.167361

Lapa, C., Hänscheid, H., Kircher, M., Schirbel, A., Wunderlich, G., Werner, R. A., Samnick, S., Kotzerke, J., Einsele, H., Buck, A. K., Wester, H.-J., & Grigoleit, G. U. (2019). Feasibility of CXCR4-Directed Radioligand Therapy in Advanced Diffuse Large B-Cell Lymphoma. Journal of Nuclear Medicine, 60(1), 60–64. https://doi.org/10.2967/jnumed.118.210997

Lapa, C., Herrmann, K., Schirbel, A., Hänscheid, H., Lückerath, K., Schottelius, M., Kircher, M., Werner, R. A., Schreder, M., Samnick, S., Kropf, S., Knop, S., Buck, A. K., Einsele, H., Wester, H.-J., & Kortüm, K. M. (2017). CXCR4-directed endoradiotherapy induces high response rates in extramedullary relapsed Multiple Myeloma. Theranostics, 7(6), 1589–1597. https://doi.org/10.7150/thno.19050

Lapa, C., Lückerath, K., Kircher, S., Hänscheid, H., Grigoleit, G. U., Rosenwald, A., Stolzenburg, A., Kropf, S., Einsele, H., Wester, H.-J., Buck, A. K., Kortüm, K. M., & Schirbel, A. (2019). Potential influence of concomitant chemotherapy on CXCR4 expression in receptor directed endoradiotherapy. British Journal of Haematology, 184(3), 440–443. https://doi.org/10.1111/bjh.15096

Maurer, S., Herhaus, P., Lippenmeyer, R., Hänscheid, H., Kircher, M., Schirbel, A., Maurer, H. C., Buck, A. K., Wester, H.-J., Einsele, H., Grigoleit, G.-U., Keller, U., & Lapa, C. (2019). Side Effects of CXC-Chemokine Receptor 4-Directed Endoradiotherapy with Pentixather Before Hematopoietic Stem Cell Transplantation. Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine, 60(10), 1399–1405. https://doi.org/10.2967/jnumed.118.223420

Schottelius, M., Osl, T., Poschenrieder, A., Hoffmann, F., Beykan, S., Hänscheid, H., Schirbel, A., Buck, A. K., Kropf, S., Schwaiger, M., Keller, U., Lassmann, M., & Wester, H.-J. (2017). [177Lu]pentixather: Comprehensive Preclinical Characterization of a First CXCR4-directed Endoradiotherapeutic Agent. Theranostics, 7(9), 2350–2362. https://doi.org/10.7150/thno.19119

Inflammatory

Li, X., Kemmer, L., Zhang, X., Kircher, M., Buck, A. K., Wester, H.-J., Hacker, M., & Lapa, C. (2018). Anti-Inflammatory Effects on Atherosclerotic Lesions Induced by CXCR4-Directed Endoradiotherapy. Journal of the American College of Cardiology, 72(1), 122–123. https://doi.org/10.1016/j.jacc.2018.04.035